Tuesday, 19 August 2014

Chronic Musculoskeletal Pain Influenced By Genetics

medwireNews: Children of parents with chronic musculoskeletal pain (CMP) are at increased risk of also suffering from such pain as adults, a large family-linkage study shows.

The association was particularly strong if both parents had CMP, and was not restricted to CMP that interfered with work ability and leisure activities, note the researchers, led by Ragnhild Lier (Norwegian University of Science and Technology, Trondheim, Norway).

“Thus, one may speculate that the occurrence of CMP in the adult offspring is strongly influenced by genetic factors”, they comment in BMC Public Health.

The researchers found a high prevalence of CMP among 11,248 parents participating in the HUNT study in 1995–97, with 56.7% of mothers and 51.4% of fathers reporting muscle or joint pain or stiffness in the past year that lasted for at least 3 consecutive months. The rate of activity-interfering CMP was somewhat lower, at 51.4% and 45.5%, respectively.

The prevalence of CMP was also high among these parent’s sons (39.3%) and daughters (47.3%) who were assessed in HUNT3 in 2006–08 when aged an average of 41 and 43 years, respectively. The corresponding rates for activity-interfering CMP were 32.2% and 25.5%.

The high prevalence of CMP in both parents and offspring, also for activity interfering CMP, suggests that not all cases are clinically relevant”, Lier and co-workers note.

They report that daughters had a 40% increased risk of having CMP if their mother had CMP and a 20% increased risk if their father had CMP, while for sons the risk was increased 40% and 30%, respectively. The risk was increased 60% for both daughters and sons if both parents had CMP. This was after adjusting for parental age, body mass index, psychological wellbeing and number of years spent in education.

Further analysis showed that CMP in the offspring was as likely to occur in those aged younger than 40 years as it was in older individuals, and the risk was similar irrespective of whether it was the mother or father who had CMP.

The researchers conclude that, although they were unable to determine the relative contribution of genetic and environmental factors, their findings “clearly demonstrate family clustering that is in agreement with a heritable component of CMP.”

medwireNews (www.medwirenews.com) is an independent clinical news service provided by Springer Healthcare Limited. © Springer Healthcare Ltd; 2014

Source: http://www.medwirenews.com/1711/105817/Pain_medicine/Chronic_musculoskeletal_pain_influenced_by_genetics.html

Thursday, 14 August 2014

Joint Pain & The Weather

People come in and they're achy and stiff. Those are the issues that keep them wanting to sit on their couch or not do anything because they hurt too much to move," says Kirk Canada, physical therapist at Hendrick Medical Center.

If Canada's description sounds familiar, you could be encountering some joint inflammation. But could the weather be exacerbating that pain?

 "A lot of the time people think just because it's when it rain that is why they're hurting, or that it's the cold that actually hurts their joints, and it's not. It's just a change in the pressure that causes the joints to hurt," Canada tells us.

He says it's not the temperature, sun or rain that's tampering with your joints, but rather it's what you can't see outside.

"Pressure from the atmosphere pushes in on that joint. When the pressure drops or the barometric pressure drops, the joints will start to push out and that's going to cause some pain in the nerves, and that's why you have more pain when that pressure drops," Canada says.

So what can you do? For starters, pay attention to your local forecast. Here on KRBC we tell you exactly what the pressure in the atmosphere is going to do.

And there's your part in staying healthy, "Keep moving, stay active, let your muscles get some movement. Help the nutrition get to the joints, stay flexible and keep active," says Canada.

Friday, 8 August 2014

MRI May be Helpful in Predicting Rheumatoid Arthritis Disease Activity

The more you and your doctor know about your RA, the better you can manage it. Doctors regularly monitor RA patient disease activity, which is the term used to refer to ongoing inflammation, symptoms, and/or joint damage in order to better manage the condition.  Information about the level of disease activity allows doctors to monitor an individual’s response to treatment and to adjust treatment as needed.

Commonly used measures of disease activity are the DAS28 (Disease Activity Score with 28 joint counts), and the Vectra DA test, which is an innovative blood test that allows doctors to test for several biological markers (or biomarkers) of RA simultaneously. Now the results of a clinical study in Europe suggest that MRI may also be a useful adjunct to monitor RA disease activity.

Physicians at the Leiden Early Arthritis Clinic have previously demonstrated that inflammation could be detected with MRI in joints without any apparent clinical inflammation in patients with early arthritis, but whether these non-swollen inflamed joints would show radiographic damage had not been explored.(1)

In the current study the doctors obtained MRIs of wrists and metacarpophalangeal and metatarsophalangeal joints in 179 patients and then took radiographs of the same joints after a year.(2) They found that arthritic joints that showed no clinical inflammation (swelling) but had evidence of subclinical inflammation on MRI had more than three times the risk of radiographic progression by 1 year.  When compared with joints having no detectable inflammation, non-swollen joints with any signs of inflammation on MRI were more likely to have evidence of joint damage as measured by radiographic progression.  The cumulative amount of MRI inflammation in non-swollen joints was comparable with that in swollen joint.

The study findings suggest that MRI could be useful for identifying joints that may show early damage even before clinical inflammation is apparent. The DAS28 score and Vectra DA test are established, fairly cost effective ways of assessing and measuring disease activity in patients with RA. It appears that MRI may also play a useful role in measuring disease activity to help doctors and patients arrive at good therapeutic choices in the overall management of RA.


Krabben A1, Stomp W, Huizinga TW, van der Heijde D, et al. Concordance between inflammation at physical examination and on MRI in patients with early arthritis. Ann Rheum Dis. 2013 Dec 12. [Epub ahead of print]
Krabben A, Stomp W, van Nies JAB, et al. MRI-detected subclinical joint inflammation is associated with radiographic progression. Ann Rheum Dis. doi:10.1136/annrheumdis-2014-205208

Source: http://awomanshealth.com/mri-may-be-helpful-in-predicting-rheumatoid-arthritis-disease-activity/

Wednesday, 6 August 2014

Matt Argall Is Excited About the Success of the New Joint Pain Formula MultiFlex Excel

MIAMI, FL--(Marketwired - Aug 5, 2014) - 

With the increasing costs for doctor visits and treatment options, remedies that can be applied by patients themselves become increasingly attractive. Developing such remedies has turned into a multi-billion dollar business with major pharmacology companies spending years of research and tons of money in inventing new medications. As a result the newly developed pills or ointments are often not much cheaper than getting treatment directly from a physician. There are some exceptions to this development though, namely when a product stems from the creative mind of a doctor who is not lead by commercial success, but who rather is searching for a cure to his own ailment.

This is what happened in the case of the new joint pain formula MultiFlex Excel, an all-natural joint supplement. Dr. Rick Argall, a seasoned chiropractor from Florida, had been suffering from knee pain for many years, trying to find a remedy to relieve the symptoms. He tried everything, from icing his joints to painkillers and anti-inflammatory creams. Frustrated by the results that were temporary at best and hesitant to undergo surgery, he consulted his wife, a chiropractor herself, to help him come up with a better approach. Upon her suggestion Dr. Argall started taking a collagen and anti-oxidant formula. Within a matter of hours he started to feel a difference, within a few days he observed a significant improvement of his symptoms and after only 10 days he was pain free. The idea for a new product was born. For the marketing, however, he would need an expert, so he turned to his son, Matt Argall, a knowledgeable and highly successful entrepreneur.

Matt Argall has extensive experience launching, managing, and marketing companies and was thrilled to help his father with the development and promotion of this new product. The result: MultiFlex Excel. The innovative joint support combines a variety of powerful and age-defying herbs that contain scientifically proven modern nutrients. MultiFlex Excel comes in three formulations - capsules, a drink, and in form of a cream. Taking only two capsules per day can stop the effects of wear and tear, which are the cause for discomfort and pain in the joints. The Joint Repair Excel powder, which needs to be mixed with water, helps to replenish the body with nutrients and the MultiFlex Excel cream is extremely effective for relieving strained muscles. Thanks to Matt, all products are now being sold online and are receiving raving reviews by satisfied customers.

Despite his many years of experience as an entrepreneur, Matt Argall was especially happy about the success of the MultiFlex project, since it gave him a chance to cooperate with his father. Born in Los Angeles, Matt and his family moved to Canada when he was five years old. The transition from one country to another brought Matt and his parents even closer together, so it was only a matter of time until they would expand this great relationship to do business together. After a few years in Canada, where his parents owned a successful chiropractic office, they moved back to the United States and have settled in Florida where Matt lives to date. Meanwhile, he has founded his own family and is a proud husband and father to a son. Nevertheless, he continues to work as an investor and consultant, always supported by his wife, Maya, whom Matt calls "his greatest inspiration".

To learn more about Matt Argall, visit: http://www.MattArgallNews.com

Source: http://www.digitaljournal.com/pr/2100578

Monday, 9 June 2014

PMS Not Linked to Hot Flashes Later, Study Finds

Women who experience premenstrual syndrome, or PMS, won't necessarily suffer from hot flashes when they go through menopause, according to a new study.

However, women who have PMS are more likely to report other common menopause complaints, such as memory and concentration problems, the researchers found.

"We were not able to detect any clear association between menopausal hot flashes and previous PMS," said study researcher Dr. Tomi Mikkola, associate professor of obstetrics and gynecology at Helsinki University Central Hospital in Finland.

"However, women with PMS are more likely to experience impaired quality of life when entering menopause," he said.

His study was published recently in the journal Menopause.

PMS refers to a group of symptoms linked to the monthly menstrual cycle. It occurs about one to two weeks before the period starts. Symptoms of PMS include mood changes, headache, breast tenderness, bloating, fatigue, sleep changes and food cravings, according to background information in the study.

Estimates of how many women suffer from PMS vary greatly. The American College of Obstetricians and Gynecologists estimates about 85 percent of women report at least one PMS symptom.

For the study, Mikkola and his colleagues included information from 120 healthy postmenopausal women who answered questions about symptoms they had experienced when they still had periods. They also answered questions about their current health and symptoms. The women were between 48 and 55 years old. None had taken hormone replacement therapy.

About 90 percent of the women said they had premenstrual symptoms earlier in their lives. About half said the symptoms hampered their ability to work well or hurt their social relations.

If the women had experienced premenstrual symptoms, at menopause, they were more likely to report problems with memory and concentration, a depressive mood, sleep problems and feeling less attractive, the study authors found.

"We do not know why PMS is linked with memory and concentration problems at menopause," Mikkola said. "However, it is possible that some women are more prone to experience both PMS and menopause symptoms more disturbing than others." That, in turn, could be related to personality, coping style, self-esteem and other factors, he said.

Dr. Margery Gass, executive director of the North American Menopause Society, reviewed the findings. "I've always thought many of the things bothering perimenopausal women are very similar to the symptoms of PMS." Perimenopause, which means "around menopause," refers to the years when a woman's body is making the transition from a regular monthly period to none.

"The study is very interesting and could help women and their [health care] providers better understand all the symptoms of menopause,'' Gass said.

Her advice for women? "Not to be surprised by these symptoms and to realize they are not going to last the rest of their lives," Gass said. "The symptoms will fade away as women get further away from their last period."

To improve PMS symptoms, experts suggest lifestyle measures such as getting regular exercise, eating a diet with plenty of whole grains, fruits and vegetables, and getting enough sleep. Over-the-counter pain relievers may help symptoms such as breast tenderness. Taking birth control pills may help reduce symptoms, too.

Source: http://www.philly.com/philly/health/topics/HealthDay688279_20140605_PMS_Not_Linked_to_Hot_Flashes_Later__Study_Finds.html

Tuesday, 20 May 2014

Report On Mental Health Suggests 'Robust' Approach To Treatment

A year in the making, a new state report recommends more funding for mental-health services, a system for tracking the availability of psychiatric beds and broadening the guidelines for forcing people into psychiatric care -- but it doesn't go as far as the legislator behind the study had hoped.

The Joint State Government Commission, the Legislature's research service, conducted the study after state Rep. Thomas Caltagirone, D-Berks County, pushed through a resolution last May requesting it.

Mr. Caltagirone, who is minority chairman of the Judiciary Committee and concerned about the growing number of people with mental illness showing up in jails and prisons, hoped the commission would recommend re-establishing some of the state hospital beds closed in recent decades as part of a national push for community-based treatment.

The commission echoed his concern about incarceration of the mentally ill, saying "it is particularly ironic" that three shuttered state hospitals ultimately were turned into prisons. However, while the commission made recommendations for keeping people with mental illness out of the justice system -- such as developing a better-funded, more robust system of community mental-health services -- it did not recommend more hospital beds.

In an email, Glenn J. Pasewicz, the commission's executive director, said "a state hospital bed is supposed to be a last resort."

"The whole notion of a robust community mental health services system is to prevent persons with mental illness from becoming so ill that institutionalization is necessary," he said.

Mr. Caltagirone said the report was a starting point but not the dynamic road map for change he had sought.

"It's not the alpha and the omega," he said. "It's just the alpha."

Mr. Caltagirone said he would consider convening workshops or hearings with some of the mental-health experts interviewed for the study to hear directly what ideas they have for improving the mental health system and ultimately will introduce legislation to move forward the initiatives he considers most relevant.

"You have to be bold and dynamic," he said, predicting that reopening hospital beds -- and diverting money from the corrections system to fund them -- is the "biggest hurdle to overcome."

Allegheny County Judge John Zottola, chairman of the state's Mental Health and Justice Advisory Committee, said the report represented a needed review of policies that are as much as 50 years old.

Deb Shoemaker, executive director of Pennsylvania Psychiatric Society, a group representing psychiatrists, said she was pleased with the report.

"The funding is the biggest issue, and it's paramount," she said.

In recommending more funding for community treatment, the commission echoed the sentiments of county officials, service providers and advocates, all of whom have lamented service cuts that followed a 10 percent reduction in state funding for mental-health services in 2012-13. It said support for community care only makes sense.

"The average cost per person in a state mental hospital in Pennsylvania is $144,072. The average cost per inmate in the state corrections institutions is $36,300," compared with an average annual cost of $2,322 for community treatment, it said.

The report did not give an opinion about how much more money is needed for community treatment.

"We did find that providers/counties would like to receive, at a minimum, restoration of the 10 percent cut from the 2013 budget, although they realize that the 10 percent would be a drop in the bucket," Mr. Pasewicz said in the email. "Also, while new money is needed, more efficient use of existing money is necessary."

The report provided additional support for some initiatives already in progress.

For example, it recommended a system for tracking availability of psychiatric beds at community hospitals. The Pennsylvania Medical Society last year called for such a system, saying patients with mental-health needs may spend hours, if not days, in emergency departments, because psychiatric beds are difficult to locate.

The study also recommended modifications to the state law regulating involuntary commitments for psychiatric care, saying the current standard for forcing a person into care is not broad enough.

State Sen. Patricia Vance, R-Cumberland County, introduced legislation in April 2013 to liberalize the standard, but the bill remains in committee. Judge Zottola said his committee has expressed interest in changes to the involuntary commitment law, but he questioned the study's proposal to include damaging property as a behavior that could force someone into care.

To give inmates stability when they leave a county jail, the commission recommended giving them up to a 30-day supply of psychiatric medications at the time of their releases. It said the state already provides departing prisoners with such a supply.

Allegheny County once provided a month's supply but cut back -- it now provides up to two weeks worth of medication and a prescription for a refill -- because of concern that medications would be sold on the street or otherwise fall into the wrong hands, said Sue Martone, the county's assistant deputy director for behavioral-health services.

The report also recommended the Legislature establish a student-loan-forgiveness program to lure more people into the mental-health field and keep them there. The federal government already offers such programs for psychiatrists, psychologists, social workers and other professionals.

Without identifying specific positions, Mr. Pasewicz said he envisions a state program for "front-line caseworkers/social workers, who comprise the bulk of personnel caught in the revolving door in human services staffing. People working in these positions are usually fresh out of college and are paid only slightly more than minimum wage."

Source: http://www.post-gazette.com/news/health/2014/05/19/PA-report-on-mental-health-suggests-robust-approach-to-treatment/stories/201405190081

Monday, 12 May 2014

How to Deal with Night Sweats, Headaches and Other Symptoms of Menopause?

BEVERLY HILLS, Calif., April 25, 2014 /PRNewswire/ -- Dealing with menopause symptoms can feel like a full-time job. Most women experience at least a few of the 45 known menopause symptoms, as identified by Dr. Shoreh Ershadi. Some suffer from debilitating symptoms that affect their day-to-day functioning. Menopause incontinence as well as hot flashes and night sweats and menopause are among the most common symptoms of menopause. Women may also experience menopause dry eyes, vaginal atrophy, and headaches and menopause. Natural products and lifestyle changes are often highly effective during this natural life transition.

Many women are interested in natural supplements such as DON'T PAUSE. These supplements offer relief from a variety of menopause symptoms without unwanted side effects. Studies have been performed on many natural ingredients, and the results are largely positive. Some herbs have been found to decrease the incidence and severity of hot flashes and night sweats while other natural ingredients can combat moodiness, irritability and dry or itchy skin. Powerful antioxidant ingredients can help restore healthier functioning overall and combat common signs of aging and menopause symptoms.

Lifestyle chances can also offer powerful relief. Menopausal women may need to keep a diary of their symptoms, which can help them identify triggers for night sweats and headaches. Avoiding these triggers can help alleviate symptoms. Women who are struggling with dry eyes menopause may benefit from moisturizing eye drops and frequent breaks from reading or screen time. Increased exercise and a nutritious diet is important for all people but especially important during menopause, when abdominal weight gain can become more common and may increase the risk of disease. Every woman is an individual and may experience variations in her symptoms. Taking a comprehensive approach that includes natural supplements and lifestyle changes is often effective against a broad range of symptoms.

The AntiAging Institute of California offers a wide selection of natural nutritional supplements, including DON'T PAUSE, which has been designed to specifically alleviate menopause symptoms. Dr. Shoreh Ershadi's research has led to the identification of 45 symptoms of menopause and the development of DON'T PAUSE, which uses a unique multi-ingredient formula that addresses both individual symptoms and the underlying cause of these symptoms.

SOURCE: The AntiAging Institute of California

Source: http://www.digitaljournal.com/pr/1874373